Endocrine Abstracts

Introduction: Parathormone (PTH) is one of the major regulator of the bone and mineral metabolism. Elevated PTH levels in patients with primary and secondary hyperparathyroidism is thought to have negative effects on the cardiovascular system. In our study, we aimed to investigate a possible relationship between plasma PTH levels and coronary atherosclerosis.Methods: Fourty-two men and 35 women, a total of 77 patients were included the study who admitted...

Aim: Thyroid tissue originates from foramen cecum located in the base of the tongue and with embryonal development it descends through thyroglossal duct to its normal location. A total or partial failure in thyroid tissue descending causes ectopic thyroid tissue. One of this ectopic region is lingual region. We presented two case of ectopic thyroid tissue.Case 1: A 18-year-old female that uses levothyroxine 100 mcg/day for hypothyroidism admitted to endo...

Introduction: Serum and intranodal levels of IGF1 and IGF-binding protein 3 levels (IGFBP3) were determined in patients with nodular thyroid diseases.Materials and methods: Demographic, clinicopathological and laboratorial caracteristics of the subjects were recorded. After performing fine needle aspiration biopsy, IGF1 and IGFBP3 levels were determined in blood and aspiration samples. Clinicopathological and laboratorial findings were analysed.<p cl...

Background: Fahr’s disease is a rare degenerative disorder characterized by symmetrical and bilateral intracranial calcification. Movement disorders are the most common symptoms of Fahr’s disease and dystonia is an uncommon presentation which accounts for only 8% of symptomatic patients.Case report: A 47 years old female admitted to emergency department with involuntary movements of extremities and anxiety. Neurological examination was normal e...

Introduction: Acromegaly is a rare disease characterized by GH and IGF1 hypersecretion and increased cardiovascular mortality. Ultrasonographic measurement of carotid intima media thickness (CIMT) gives substantial information about early atherosclerosis. We aimed to evaluate CIMT and its determinants in a group of acromegaly patient.Patients and methods: Forty-four acromegaly patient and 43 age, sex and body mass index (BMI) matched healthy controls wer...

Aim: The role of statins on thyroid cell proliferation is of clinical interest. In this study, we investigated the effect of atorvastatin on papillary thyroid cell line (B-CPAP) and normal thyroid (Nthy-ori3-1) cell lines.Materials and methods: In this in vitro study, B-CPAP and Nthy-ori3-1 cell lines were treated with atorvastatin at 12.5, 25, 50, 100, 200 μM concentrations. At 48 and 72 h MTT, electron microscopy and immunohistochemistry we...

Objective: This study aimed to determine the diabetes care profile and diabetes management in individuals with type 2 diabetes.Methods: The population of the cross-sectional study consisted of individuals with Type 2 diabetes who received treatment in the internal medicine services of Public Hospitals in a province, and 377 individuals who met the inclusion criteria constituted the sample. Data was obtained using the Information Form, the Summary of Diab...

Background: Prolactinoma is the most common functioning pituitary adenoma. Subclinical atherosclerosis and cardiovascular risk in patients with prolactinoma were reported but have not been clarified yet.Aim: Our study aims to compare prolactinoma patients with a control group in terms of lipid profile, body fat distribution, and subclinical atherosclerosis markers.Methods: This single-center, prospective study included 32 patients ...

Primary hyperparathyroidism in the most common cause of hypercalcemia. 87% of the cases present with single adenoma, 9% of them have hyperplasia, while multiple adenomas and parathyroid malignancy are detected in 3 and 1% of the cases, respectively. Although it is rare, parathyroid adenomas may be ectopic. The most common locations for ectopic parathyroid adenomas are thymus, tracheaesophageal cleft, carotis sheet, intrathyroidal and paraesophageal area. In this study, we aime...

Aim: There are some studies suggesting that the risk of developing cancers,especially thyroid cancer, is increased in the patients with acromegaly. The prevalence of thyroid cancer is 1.2-10.6% among the patients with acromegaly. In this study, we aimed to evaluate clinical and histopathologic characteristics of thyroid cancer among the patients with acromegaly.Method: We retrospectively evaluated the patients with acromegaly who had been followed-up by ...